侵入性血压 - 临床前研究的基本原理和最佳实践
- 6 Dec 17
Tom Smith presents the fundamentals of invasive blood pressure measurements for preclinical research, including technical considerations, experimental design, and best-practices that lead to accurate and consistent results.
临床前和临床科学家可以使用许多选择，包括用于研究的血压数据集，包括带有流体填充导管的一次性换能器，具有高富达的固态导管和非侵入性测量系统。这些方法中的每一种都提供了一种实验方法，以及可能对研究科学家所期望的结果的理想程度。对于使用小鼠等小型实验室动物的实验，了解如何将血压数据中所需的终点与合适的技术联系起来至关重要。该网络研讨会向与会者提供了对全身血管系统压力测量物理学的基本了解，并探讨了为什么经常需要实验室成功的固态测量技术。
在这项由AdinStruments赞助的网络研讨会中，Wake Forest医学院的骨科外科教授Tom Smith，微外科和血管压力测量技术的专家讨论了血管测量中压力测量的基本特性，包括固体和物理学背后的固体物理学。状态测量法。此外，他解释了与准确性，一致性和研究结果有关的高保真固态导管的重要性和影响。
Thomas L. Smith, Ph.D
Professor, Orthopaedic Surgery Physiology & Pharmacology, Institute for Regenerative Medicine, Biomedical Engineering, Wake Forest School of Medicine
Tom Smith is a professor of Orthopaedic Surgery at the Wake Forest School of Medicine. His research interests range from musculoskeletal adaptation and injury, to Electric Stimulation Therapy, and the study of neuromuscular agents. In collaboration with the Wake Forest Institute for Regenerative Medicine, he is currently researching the use of tissue engineered constructs for repair of peripheral nerve gaps following injury, tissue engineered allografts for ACL, tendon and meniscus repairs, and murine models of myocardial infarction to test stem cell therapies utilizing coronary artery ligations performed as survival surgeries in mice.
