×

光遗传学

光遗传学

光遗传学是一种相对较新的技术,它使用光精确地操纵神经活动(神经调节)。它涉及使用OPSIN(光敏蛋白)转染靶细胞,并用可见光的脉冲使它们令人兴奋或沉默。与常规的电刺激相比,光遗传学减少了相邻细胞的激活,从而确保刺激是高度靶向的,并导致特定的生理和行为效应。

The Kaha Sciences Optogenetics telemeter from ADInstruments is the first fully implantable, controllable optogenetics stimulator for use in rats that can also record biopotential (EEG, ECG, EMG) signals. An ideal solution for chronic and therapeutic research applications including heart pacing, seizure suppression and reducing abnormal motor symptoms. This telemeter allows researchers to apply extended optogenetic stimulation protocols and record quantitative biopotential data in long-term experiments without the restrictions of battery power and tethers.

脑电在鼠标中显示癫痫发作

产品和解决方案

Wireless - power and data recording

Wireless - power and data recording

High fidelity<br /> signals

High fidelity
signals

Simultaneous stimulation<br /> and recording

Simultaneous stimulation
和录音

24/7连续<br />录音

24/7连续
记录

基于遥测的光遗传学的优势

尽管将通道旋转蛋白转染为特定的细胞类型方面取得了重大进展,但传统上为刺激提供光的技术依赖于束缚或头部安装的系统。基于遥测的光遗传学研究对这些替代方法的优势使这是慢性和治疗研究研究的理想选择。

有意识的– Anesthesia affects most physiological control systems and can significantly confound your results. Telemetry allows data to be collected from conscious animals after they have recovered from surgery and enables cognitive and behavioral studies not possible under anesthesia.

Unrestrained- 限制动物会诱发应激,从而影响正常的生理功能和记录的数据。遥测允许从其家居中的动物收集数据,而不会导致研究人员或处理的存在压力。缺乏系数也减轻了维护/替代负担。

Long-term– Offers truly chronic recording over days, weeks or months. Researchers can develop stimulation protocol while studying biological rhythms and follow the development of pathology as it occurs. Within animal design strengthens the statistical power of a study and can reduce group sizes.

完全植入- The full surgical implantation of telemeters and animal recovery process prior to recording ensures there are no exposed wounds or sites for possible infections, improving animal welfare.

Quality Data- Reduced noise and movement artefacts from amplifiers being so close to the point of measurement and no external tether acting as an aerial to attract noise.

遥测的更多优势

Advantages of Kaha Sciences Telemetry
Extensively used globally in academic and research institutions as well as biotechnology and pharmaceutical companies, Kaha systems combine high fidelity digital telemetry with patented wireless power technology to create high-quality solutions for your physiological monitoring needs. Paired with PowerLab and LabChart/LabChart Lightning, this solution sets the new standard in quality and power for implantable, wireless telemetry in rats and mice. Measure true high-fidelity signals such as ventricular and arterial pressures, sympathetic nerve activity (SNA), biopotentials (e.g. ECG, EMG & EEG), tissue oxygen, and optogenetics stimulating and recording.

Learn more about Kaha Sciences

In conjunction with our solutions shown below, any device with an analog output (+/- 10V) can be connected to aPowerLabdata acquisition system for synchronization of the event inldsports体育资讯 ,包括其他可植入物品(血管通道端口,渗透泵,输液泵)。这为您提供了更大的灵活性和将数据流集成到一个地方的能力。

Typical Studies

Parkinson's Disease

Epilepsy

Cardiac Dysfunction

沮丧

疼痛

Retina Degeneration

Auditory Dysfunction

Flexible Data Acquisition

adinstrumentssystems provide an integrated solution to advance life science research. With the combination ofldsports体育资讯 orld乐动官网 analysis software and aPowerLabdata acquisition unit, you have the flexibility to collect and synchronize a wide range of signals for analysis. We also offer a range of LabChart compatible solutions able to stream directly in LabChart.

LabChart

LabChart

Enabling Discovery

LabChart数据分析软件为您的所有录制设备共同努力创建一个平台,使您可以同时从多个来源获取生物信号,并在实验展开时应用高级计算和图。了解有关LabChart和Optogenotics的更多信息»

Data acquisition and analysisre-imagined。以无限的自由和灵活性做出独特的发现。ld乐动官网

PowerLab

PowerLab

具有完整性的数据

High-performance data acquisition hardware designed for life science research. PowerLab is engineered for precise, consistent, reliable data acquisition, giving you the reproducible data you need while meeting the strictest international safety standards.学到更多 ”

PowerLab C

PowerLab C

Re-engineered for
unparalleled flexibility

A modular data acquisition foundation system that provides unparalleled flexibility for researchers looking to invest in customizable, reliable solutions for both now, and in the future.学到更多 ”

您的所有分析在一个地方

ldsports体育资讯 软件是专门为生命科学数据设计的,可为数据显示和分析选项提供多达32个渠道,这些渠道功能强大且易于使用。借助ADI和LABCHART兼容硬件的自动认可,多窗口视图,一个触摸录制,来自多个设备的同时录制,专门的预配置设置,易于共享选项和可以自定义的界面,以仅显示您想要使用的功能。

  • 脑电在鼠标中显示癫痫发作

    脑电在鼠标中显示癫痫发作

功能和附加组件

Additional acquisition and analysis features and add-ons to support your Optogenetics studies:

Simultaneously sample and compare telemetry data with other physiological signals.

One of the great features of combining DSI PhysioTel™ Implants with LabChart is the ability to simultaneously sample from a PowerLab. Your data is synchronized (+-20ms) with your telemetry implants, allowing you to combine implanted signals with other physiological parameters such as respiratory signals.

×
LabChartLightning
播放视频

数据采集和分析化学。

以无限的自由和灵活性做出独特的发现。

立即免费尝试Labchart Lightning

This site is protected by reCAPTCHA and the Google隐私政策andTerms of Service申请。

Oops, something went wrong...

Thanks, we've sent you an email with instructions on how to start your trial.

Request a demo

Thank you for your interest in光遗传学。Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the联系人页面。

×

Ask a question

Thank you for your interest in光遗传学。Please complete and submit the form below and an ADInstruments representative will aim to get in touch within one working day. If you’d like to speak to someone immediately, office contact information is available from the联系人页面。

×
Ask a question×
Baidu