Kaha Sciences telemetry solutions将无线功率和最先进的压力传感器技术结合在一起，以提供无与伦比的精度和长期记录。
With options to measure pressure (arterial, venous, and ventricular), ECG, sympathetic nerve activity, and tissue oxygen concentrations, 24/7 over the course of your experiment - Kaha Sciences' telemeters allow you to measure a range of cardiovascular signals to meet your research needs.
有关的：在研究中使用遥测的好处»
KAHA科学遥测 - 心血管应用：
压力
Kaha Sciences rat pressure telemeters use the Millar Mikro-Tip® solid-state sensor technology, at the catheter tip to allow high fidelity, accurate, and repeatable pressure recordings. The 2 Fr (0.66 mm) sensor can record a range of pressures including; arterial blood pressure, venous pressure, and ventricular pressure.
有关的：Benefits of using solid-state pressure sensors »
单人可以使用遥测器（TRM54P) or dual (trm54pp9)导管长度,custome 15或25厘米rs can tailor their experiment and record up to two pressures with one telemeter.
信号的质量和准确性允许对动物的基本特征提取（例如收缩期，舒张压）的信心，但也促进了更复杂的分析，例如来自LVP的BP和DP/DT计算的光谱分析和心脏输出。
Read more:Tips and Tricks for Successful Rat Telemetry Blood Pressure Recordings »
出版物：
- Sachdeva, R.et al.Noninvasive Neuroprosthesis Promotes Cardiovascular Recovery After Spinal Cord Injury. Neurotherapeutics (2021).
- Han，J.-C。et al.Left-Ventricular Energetics in Pulmonary Arterial Hypertension-Induced Right-Ventricular Hypertrophic Failure.正面。生理学。8，1115（2018）。
- Griffiths, P. R.et al.鼻腹侧髓质蛋白受体的阻断不会减轻SHR和L名称诱导的高血压大鼠的动脉压。正面。生理学。9, 1488 (2018).
- Stehlin，E。et al.Chronic measurement of left ventricular pressure in freely moving rats.J. Appl. Physiol.115, 1672–1682 (2013).
ECG
生物电位遥测者（TR50B和TR50BB) allow the long-term recording ofECG,emg，或者脑电in freely moving rats. Our wireless power technology supports long-term, continuous recording at high sampling rates (2kHz) which is ideal for monitoring spontaneous pathophysiological activity, such asectopic beats或者the generation ofarrhythmia.
TheTRM54PB遥测者还允许客户组合ECG和压力来自同一动物的测量以评估心脏和心血管功能。
出版物：
- Kim, N. K., Wolfson, D., Fernandez, N., Shin, M. & Cho, H. C. A rat model of complete atrioventricular block recapitulates clinical indices of bradycardia and provides a platform to test disease-modifying therapies.Sci. Rep.9, 6930 (2019).
- Zhang, D.et al.降低的n型Ca2+Channels in Atrioventricular Ganglion Neurons Are Involved in Ventricular Arrhythmogenesis.J. Am。心脏协会。7, (2018).
Sympathetic Nerve Activity (SNA)
TheTRM56SP遥测器允许用户同时记录同一动物的同时血压和SNA。这在研究高血压和心血管控制的发展方面特别有用。
SNA铅的输入范围为±60µV，非常适合从细，外周自主神经记录活动。
出版物：
- McBryde，F。D.，Liu，B。H.，Roloff，E。V.，Kasparov，S。＆Paton，J。F. R.下丘脑旁腔内核神经元氧化物氧化物合酶合酶活性是意识Wistar大鼠肾交感神经的主要决定因素。经验。生理学。103, 419–428 (2018).
- Salman, I. M., Sarma Kandukuri, D., Harrison, J. L., Hildreth, C. M. & Phillips, J. K. Direct conscious telemetry recordings demonstrate increased renal sympathetic nerve activity in rats with chronic kidney disease.正面。生理学。6, (2015).
组织氧
TheTR57Y tissue oxygen telemeter是市场上唯一可以实时测量有意识大鼠的组织氧浓度的设备。
The telemeter uses a stable carbon paste electrode and can measure localischemia和组织代谢活性在里面肾和脑. Combined with our wireless power technology researchers have been able to assess circadian variability in kidney tissue oxygen thanks to the ability to record 24/7.
有关的：组织氧遥测 - 它如何工作，为什么对您的研究有益？»
出版物：
- Thakkar, P.C.et al.Therapeutic Relevance of Elevated Blood Pressure After Ischemic Stroke in the Hypertensive Rats.Hypertension.75, 740–747 (2020)
- Y. Adamovichet al.Oxygen, and Carbon Dioxide Rhythms Are Circadian Clock Controlled and Differentially Directed by Behavioral Signals.细胞代谢。29，1092-1103.E3（2019）。
- Emans，T。W.，Janssen，B。J.，Joles，J。A.＆Krediet，C。T. P. P. P.昼夜节律在大鼠的肾脏组织中氧合。正面。生理学。8, (2017).
For more information about卡哈科学遥测者, or to discuss your specific research application please contact your nearestADInstruments support representative.
Related resources:
客户快照-Fiona McBryde博士：使用遥测来了解中风的生理学»
Tips and tricks for long-term recordings of left ventricular pressure in rats »
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